RESEARCH INTERESTS

· Self-assembled Nanoporous Membrane and Its Biomedical Applications (Separation, Drug Delivery, and Sensing)

· Soft Template based Nanomaterials Fabrication for Sensing Device

· Microneedle based Biotechnology Including Surgical Tape, Drug Delivery, and Medical Device

· Biomaterials for Tissue Adhesives, Drug Delivery, and Regenerative Medicine

ONGOING PROJECTS

· Worm-inspired Microneedle Adhesive for Wound Healing

· Nanoporous Membrane for Virus Filtration

EDUCATION

Ph. D. Pohang University of Science & Technology , South Korea ( Polymer Engineering), Advisor: Jin Kon Kim

M. Eng. Pohang University of Science & Technology , South Korea ( Polymer Engineering), Advisor: Jin Kon Kim

B. Eng. Kyungpook National University, South Korea, Double Major (Environmental Engineering / Chemical Engineering)

EXPERIENCE

PUBLICATIONS

Peer-Reviewed Journal Publications

18. S. R. Shin, B. Aghaei-Ghaerh-Bolagh, T. T. Dang, S. N. Topkaya, X. Gao, S. Y. Yang , S. M. Jung, J. H. Oh, M. R. Dokmeci, X. (Shirley) Tang*, and A. Khademhosseini* Advanced Materials (in press).

17. E.-S. Kim, D. S. Jang, S. Y. Yang , M. N. Lee, K. S. Jin, H. J. Cha, J. K. Kim, Y. C. Sung and K. Y. Choi* “Controlled release of human growth hormone fused with a human hybrid Fc fragment through a nanoporous polymer membrane”Nanoscale 5, 4262-4269 (May 21, 2013).

16. S. Y. Yang , E. D. O'Cearbhaill, G. C. Sisk, K. M. Park, W. K. Cho, M. Villiger, B. E. Bouma, B. Pomahac, and J. M. Karp* “A Bio-Inspired Swellable Microneedle Adhesive for Mechanical Interlocking with Tissue” Nature Communications 4, 1702 (Apr. 16, 2013). (This work is selected as Featured Image in Nature Communications main homepage and introduced at Research Highlights in Nature (doi:10.1038/496400d). It is also highlighted as News in Science, Nature Medicine, BBC, Fox News, LA times, National Geographic, NIH Director’s Blog, and so on.

15. S. Y. Yang ^† , E.-S. Kim ^† , G. Jeon, K. Y. Choi*, and J. K. Kim* “Enhanced Adhesion of Osteoblastic Cells on Polystyrene Films by Independent Control of Surface Topography and Wettability” Materials Science and Engineering C 33, 1689-1695 (Apr. 1, 2013). ^† Co-first author

14. W. K. Cho, J. A. Ankrum, D. Guo, S. A. Chester, S. Y. Yang , A. Kashyap, G. A. Campbell, R. J. Wood, R. K. Rijal, R. Karnik, R. Langer* and J. M. Karp* “Microstructured barbs on the North American porcupine quill enable easy tissue penetration” Proc. Natl. Acad. Sci. U.S.A 109, 21289-21294 (Dec. 26, 2012). (This work is selected as Cover Picture ).

13. S. Y. Yang , G. Jeon, and J. K. Kim* “A high density array of free standing alumina nanotubes aligned vertically on solid substrates in a large area” Journal of Materials Chemistry 22, 23017-23021 (Nov. 21, 2012) .

12. C. Xu, Y. C. Poh, I. Roes, E. O’Cearbhaill, M. Matthi, L. Mu, S. Y. Yang , D. Mirand, D. Irimia, J. M. Karp* “A Portable Chemotaxis Platform for Short and Long Term Analysis” PLoS One 7, e44995 (Sep. 17, 2012) .

11. G. Jeon, S. Y. Yang , and J. K. Kim* “Functional nanoporous membranes for drug delivery” Journal of Materials Chemistry 22, 14814-14834 (Aug. 14. 2012) .

10. S. Y. Yang ^† , S. Son ^† , S. Jang, H. Kim, G. Jeon, W. J. Kim*, and J. K. Kim* “DNA-Functionalized Nanochannels for SNP Detection” Nano Letters 11, 1032-1035 (Mar. 9. 2012) . ^† Co-first author

9. G. Jeon, S. Y. Yang , J. Byun, J. K. Kim* “Electrically Actuatable Smart Nanoporous Membrane for Pulsatile Drug Release” Nano Letters 11, 1284-1288 (Mar. 9. 2012) .

8. Y. H. Jang, S. Y. Yang , Y. J. Jang, C. Park, J. K. Kim, and D. H. Kim* “Ultrahigh Density Arrays of Toroidal ZnO Nanostructures by One-Step Cooperative Self-Assembly Processes: Mechanism of Structural Evolution and Hybridization with Au Nanoparticles” Chemistry - A European Journal 17, 2068-2076 (Feb. 11, 2011) .

7. J. K. Kim*, S. Y. Yang , Y. Kim, Y. Lee “Functional Nanomaterials Based on Block Copolymer Self-assembly” Progress in Polymer Science 35, 1325-1349 (Nov. 1, 2010).

6. S. Y. Yang ^† , J.-A Yang ^† , E. S. Kim, G. Jeon, E. J. Oh, K. Y. Choi, S. K. Hahn*, and J. K. Kim* “Single-File Diffusion of Protein Drugs through Cylindrical Nanochannels” ACS Nano 4, 3817-3822 (July 27, 2010). ^† Co-first author (Highlighted in the "Perspective" of the same issue (ACS Nano 4, 3548)).

5. W. Joo, S. Y. Yang , J. K. Kim * , H. Jinnai, “Nanohole Structure in Polystyrene- block -poly(methyl methacrylate) /poly(methyl methacrylate) Mixture Film” Langmuir 24, 12612-12617 (Nov. 4, 2008).

4. S. Y. Yang , J. Park, J. Yoon, M. Ree, S. K. Jang, and J. K. Kim*, “Virus Filtration Membrane prepared by Nanoporous Block Copolymer with dimensional stability under high pressures and excellent solvent resistance” Advanced Functional Materials 18, 1371-1377 (May 9, 2008).

3. E. J. Oh, J. Yang, S. Y. Yang J. K. Kim, S. K. Hahn*, “Drug Delivery Systems for Protein Therapeutics“, Polymer Science and Technology 18, 444-449 (Oct. 1, 2007). (Review in Korean)

2. J. Yoon ^† , S. Y. Yang ^† , K. Heo, B. Lee, W.-C. Joo, J. K. Kim * , M. Ree * , “Nondestructive, Quantitative Synchtron Grazing Incidence X-ray Scattering Analysis of Cylindrical Nanostructures in Supported Thin Films”, Journal of Applied Crystallography 40, 305-312 (Apr. 1, 2007). ^† Co-first author

1. S. Y. Yang , I. Ryu, H. Y. Kim, S. K. Jang * , J. K. Kim * and T. P. Russell, “Nanoporous Membrane with Ultrahigh Selectivity and Flux Suitable for Filtration of Viruses”, Advanced Materials 18, 709-712 (Mar. 17, 2006).

Proceedings of Conferences

3. S. Y. Yang, J.-A Yang, S. K. Hahn, and J. K. Kim, “Controlled Release of Protein Drugs Through the Cylindrical Nanochannel” PMSE Preprint 101, 995 (Aug. 2009).

2. J. I. Lee, S. Y. Yang , J. K. Kim, “Nano-structured Materials Prepared by Block Copolymer Thin Films for Photovoltaic Cells And Virus Filtration” PMSE Preprint 95, 931 (Aug. 2006).

1. J. I. Lee, S. Y. Yang , J. A. Jang, U. Jeong, J. K. Kim, “Nanostructured Materials by Block Copolymer Thin Film” Polymer Preprint 46, 565 (Aug. 2005).

PATENTS AND PATENT APPLICATIONS

6. S. Y. Yang , E. D. O'Cearbhaill, J. M. Karp, B. Pomahac “Swellable adhesive needles” US patent application61/759,901 (Feb.1, 2013).

5. J. K. Kim, S. Jang, S. Y. Yang , G, Jeon, W. J. Kim, S. Son, H. Kim “Membrane and method of fabricating the same”South Korea patent application 10-2011-0080828 (Aug. 12, 2011) .

4. S. Y. Yang , J. K. Kim, G, Jeon, J. Byun, J. Y. Sohn, C.-S. Lee, H. J. Kim “Nanoporous membrane responsive to electrical stimulation and method for manufacturing the same” South Korea patent application 10-2011-0063990 (June 29, 2011 ) & US patent application , 13/247,615 (Sep. 28, 2011).

3. S. Y. Yang , J. K. Kim, G, Jeon, J. Byun, J. Y. Sohn, C.-S. Lee, H. J. Kim “Method of manufacturing vertically aligned nanotubes, method of manufacturing sensor structure, and sensor element manufactured thereby” South Korea patent 10-1134184 (Mar. 30, 2012) & US patent 8,377,730 (Feb. 19, 2013 ).

2. S. Y. Yang , J. K. Kim, M. S. Park, I. Ryu, S. K. Jang “Nanoporous membrane, process of fabricating the same and device for controlled release of biopharmaceuticals comprising the same” South Korea patent 10-0964504 (June 10, 2010) & US patent 7,935,416 (May 3, 2011).

1. S. Y. Yang , J. K. Kim, M. S. Park, I. Ryu, S. K. Jang “Nanoporous membrane and process for fabrication of the same”South Korea patent 10-0721430 (May 17, 2007) & US patent 7, 438,193 (Oct. 21, 2008).

PRESENTATIONS (SELECTED)

9. S. Y. Yang , E. D. O'Cearbhaill, G. C. Sisk, K. M. Park, W. K. Cho, M. Villiger, B. E. Bouma, B. Pomahac, and J. M. Karp “A Bio-Inspired Microneedle Adhesive for Skin Graft Fixation”, 2013 MIT Polymer Day , Cambridge, MA, USA (Mar. 2013). (Poster presentation)

8. S. Y. Yang , J.-A Yang, E. S. Kim, G. Jeon, E. J. Oh, K. Y. Choi, S. K. Hahn, and J. K. Kim, “Nanoporous Membrane with Block Copolymer Thin Film for Protein Drug Delivery”, APS 2010 March meeting , Portland, USA (Mar. 2010). (Oral presentation)

7. S. Y. Yang , J. A. Yang, S. K. Hahn and J. K. Kim, “Single File Diffusion of Protein Drugs through Cylindrical Nanochannel”, MRS 2008 fall meeting , Boston, USA (Dec. 2008). (Oral presentation)

6. S. Y. Yang , “Nanoporous Membranes with Ultrahigh Selectivity and Flux Suitable for Filtration of Viruses”, First HOPE Meeting , p53, Tsukuba, Japan (Feb. 2008). (Oral presentation)

5. S. Y. Yang , J. Park, S. K. Jang, J. K. Kim “Nanoporous Membranes for virus filtration with very high flux and selectivity”ECS 211 ^th meeting , Chicago, USA (May 2007). (Oral presentation)

4. S. Y. Yang , I. Ryu, S. K. Jang, J. K. Kim, T. P. Russell “Nanoporous Membranes for virus filtration with high flux” MRS 2007 spring meeting , San Francisco, USA (Mar. 2007). (Oral presentation)

3. S. Y. Yang , I. Ryu, S. K. Jang and J. K. Kim “Nanoporous Memberanes Using Thin Film of Block Copolymer for Virus Filtration” AsiaNano 2006 , Busan, Korea (Nov. 2006). (Oral presentation)

2. S. Y. Yang , W. Joo, and J. K. Kim “Analysis of Nanoporous Structures in Block Copolymer Thin Films”, Korean institute of metals and materials fall meeting , Jeju island, Korea (Oct. 2006). (Invited talk)

1. S. Y. Yang , I. Ryu, H. Y. Kim, S. K. Jang, and J. K. Kim, “Nanoporous Membrane with Ultrahigh Selectivity and Flux Suitable for Filtration of Viruses”, International Congress on Membranes and Membrane Processes , Seoul, Korea (Aug. 2005). (Poster presentation)

Press

사이언스타임즈 http://www.sciencetimes.co.kr/article.do?atidx=0000069996

한계레 ( 사이언스 온 ) http://scienceon.hani.co.kr/media/93668

Nature: doi:10.1038/496400d

Nature Medicine: doi:10.1038/nm0213-124

Science: http://news.sciencemag.org/sciencenow/2013/04/scienceshot-parasite-inspires-su-1.html?ref=hp

BBC News: http://www.bbc.co.uk/news/health-22164451

Fox News: http://www.foxnews.com/science/2013/04/16/parasitic-worm-inspires-surgical-technique/

LA Times: http://www.latimes.com/news/science/sciencenow/la-sci-sn-spiny-headed-parasitic-worm-skin-graft-bioinspired-20130416,0,7980109.story

National Geographic: http://phenomena.nationalgeographic.com/2013/04/16/parasitic-worm-inspires-better-sticky-medical-tape/

The Scientist Magazine: http://www.the-scientist.com/?articles.view/articleNo/36093/title/Sticking-Power/

NIH Director's blog: http://directorsblog.nih.gov/spiny-worm-inspires-next-gen-band-aid/#more-1247

http://youtu.be/9T18POXn_Rc ( 마이크로바늘을 이용한 조직접착제 동영상 )

http://www.ivanhoe.com/contentclientvideo/MB_videozip/mb3671.mov ( 마이크로바늘 접착제가 신바이오 소재로 소개된동영상 )