1978.03. - 19 82.02. 서울대학교 (이학사-식물병리학)

19 84.09. - 19 91.05. 미국 Univ. of Texas at Austin (이학박사-분자생물학)

19 85.09. - 19 91.02. 미국 Univ. of Texas at Austin 강의 및 연구조교

19 91.03. - 199 4.03. 미국 Univ. of Texas at Austin 박사후연구원

19 94.03. - 19 96.03. 부산대학교 자연과학대학 분자생물학과 전임강사

19 96.04. - 2000.03. 부산대학교 자연과학대학 분자생물학과 조교수

2000.04. - 2005.03. 부산대학교 자연과학대학 분자생물학과 부교수

2005.04. - 현 재 부산대학교 자연과학대학 분자생물학과 교수

1. 미토콘드리아 기능이상에 의한 암 악성화 기전 연구

2. 암 혈관신생의 분자 기전 및 제어 기술 연구

1. Park SY, Jang WJ, Yi EY, Jang JY, Jung Y, Jeong JW, Kim YJ (2010) Melatonin suppresses tumor angiogenesis by inhibiting HIF-1 stabilization under hypoxia. J Pineal Res (in press)

2. Park SY, Seo EH, Song HS, Jung SY, Lee YK, Yi KY, Yoo SE, Kim YJ (2008) KR-31831, benzopyran derivative, inhibits VEGF-induced angiogenesis of HUVECs through suppressing KDR expression. Int J Oncol. 32:1311-1315

3. Kim CH, Han SI, Lee SY, Youk HS, Moon JY, Duong HQ, Park MJ, Joo YM, Park HG, Kim YJ , Yoo MA, Lim SC, Kang HS (2007) Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells. J Cell Physiol. 211:371-385

4. Jeon H, Kim H, Choi D, Kim D, Park SY, Kim YJ, Kim YM, Jung Y (2007) Quercetin activates an angiogenic pathway, hypoxia inducible factor (HIF)-1-vascular endothelial growth factor, by inhibiting HIF-prolyl hydroxylase: a structural analysis of quercetin for inhibiting HIF-prolyl hydroxylase. Mol Pharmacol. 71:1676-1684

5. Yi EY, Park SY, Song HS, Son MJ, Yi KY, Yoo SE, and Kim YJ (2006) KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in vitro angiogenesis. Exp Mol Med 38: 502-508

6. Jeon JW, Song HS, Moon EJ, Park SY, Son MJ, Jung SY, Kim JT, Nam DH, Choi-Miura NH, Kim KW, and Kim YJ (2006) Anti-angiogenic action of plasma hyaluronan binding protein in human umbilical vein endothelial cells. Int J Oncol. 29: 209-215

7. Lee SH, Son MJ, Oh SH, Rho SB, Park K, Kim YJ , Park MS, Lee JH (2005) Thymosin β 10 Inhibits Angiogenesis and Tumor Growth by Interfering with Ras Function. Cancer Res. 65: 137-148

8. Yi EY, Jeong EJ, Song HS, Lee MS, Kang DW, Joo JH, Kwon HS, Lee SH, Park SK, Chung SG, Cho EH and Kim YJ (2004) Anti-angiogenic and anti-tumor apoptotic activities of SJ-8002, a new piperazine derivative. Int J Oncol. 25: 365-372

9. Yi EY, Jeong EJ, Song HS, Lee MS, Kang DW, Joo JH, Kwon HS, Lee SH, Park SK, Chung SG, Cho EH and Kim YJ (2004) Anti-angiogenic and anti-tumor apoptotic activities of SJ-8002, a new piperazine derivative. Int J Oncol. 25: 365-372

10. Lee SW, Kim WJ, Choi YK, Song HS, Son MJ, Gelman IH, Kim YJ , Kim KW (2003) SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier, Nature med 9: 900-906

11. Park SY, Seo SB, Lee SJ, Na JG and Kim YJ (2001) Mutation in PMR1, a Ca(2+)-ATPase in Golgi, confers salt tolerance in Saccharomyces cerevisiae by inducing expression of PMR2, an Na(+)-ATPase in plasma membrane. J Biol Chem. 276: 28694-28699

1978.03. -
19
82.02. 서울대학교 (이학사-식물병리학)

19
84.09. -
19
91.05.
미국 Univ. of Texas at Austin (이학박사-분자생물학)

19
85.09. -
19
91.02.
미국 Univ. of Texas at Austin 강의 및 연구조교

19
91.03. -
199
4.03.
미국 Univ. of Texas at Austin 박사후연구원

19
94.03. -
19
96.03.
부산대학교 자연과학대학 분자생물학과 전임강사

19
96.04. - 2000.03. 부산대학교 자연과학대학 분자생물학과 조교수

2000.04. - 2005.03. 부산대학교 자연과학대학 분자생물학과 부교수

2005.04. - 현 재 부산대학교 자연과학대학 분자생물학과 교수

?

1. 미토콘드리아 기능이상에 의한 암 악성화 기전 연구



2. 암 혈관신생의 분자 기전 및 제어 기술 연구

?

1. Park SY, Jang WJ, Yi EY, Jang JY, Jung Y, Jeong JW, Kim YJ (2010)
Melatonin suppresses tumor angiogenesis by inhibiting HIF-1
stabilization under hypoxia.
J Pineal Res
(in press)

2. Park SY, Seo EH, Song HS, Jung SY, Lee YK, Yi KY, Yoo SE,
Kim
YJ

(2008) KR-31831, benzopyran derivative, inhibits VEGF-induced angiogenesis of
HUVECs through suppressing KDR expression.
Int J Oncol.
32:1311-1315

3. Kim CH, Han SI, Lee SY, Youk HS, Moon JY, Duong HQ, Park MJ, Joo
YM, Park HG,
Kim YJ
, Yoo MA, Lim SC,
Kang HS (2007)
Protein kinase C-ERK1/2 signal pathway switches glucose
depletion-induced necrosis to apoptosis by regulating superoxide dismutases and
suppressing reactive oxygen species production in A549 lung cancer cells.
J Cell Physiol.
211:371-385

4. Jeon H, Kim H, Choi D, Kim D, Park SY, Kim YJ, Kim YM, Jung Y
(2007) Quercetin activates an angiogenic pathway, hypoxia inducible factor
(HIF)-1-vascular endothelial growth factor, by inhibiting HIF-prolyl
hydroxylase: a structural analysis of quercetin for inhibiting HIF-prolyl
hydroxylase.
Mol Pharmacol.
71:1676-1684

5. Yi EY, Park SY, Song HS, Son MJ, Yi KY, Yoo SE, and
Kim
YJ

(2006) KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in
vitro angiogenesis.
Exp Mol Med
38: 502-508

6. Jeon JW, Song HS, Moon EJ, Park SY, Son MJ, Jung SY, Kim JT, Nam
DH, Choi-Miura NH, Kim KW, and Kim YJ (2006)
Anti-angiogenic
action of plasma hyaluronan binding protein in human umbilical vein endothelial
cells.
Int J Oncol.
29: 209-215

7. Lee SH, Son MJ, Oh SH, Rho SB, Park K,
Kim
YJ
,
Park MS, Lee JH (2005) Thymosin β
10
Inhibits Angiogenesis and Tumor Growth by Interfering with Ras
Function.
Cancer Res.
65: 137-148

8. Yi EY, Jeong EJ, Song HS, Lee MS, Kang DW, Joo JH, Kwon HS, Lee
SH, Park SK, Chung SG, Cho EH and
Kim
YJ

(2004)
Anti-angiogenic and anti-tumor apoptotic activities of SJ-8002, a new
piperazine derivative.
Int J Oncol.
25: 365-372

9. Yi EY, Jeong EJ, Song HS, Lee MS, Kang DW, Joo JH, Kwon HS, Lee
SH, Park SK, Chung SG, Cho EH and Kim YJ (2004)
Anti-angiogenic
and anti-tumor apoptotic activities of SJ-8002, a new piperazine derivative.
Int J Oncol.
25: 365-372

10. Lee SW, Kim WJ, Choi YK, Song HS, Son MJ, Gelman IH,
Kim
YJ
,
Kim KW (2003)
SSeCKS regulates angiogenesis and tight junction formation in
blood-brain barrier,
Nature med
9: 900-906

11. Park SY, Seo SB, Lee SJ, Na JG and Kim YJ (2001)
Mutation in PMR1,
a Ca(2+)-ATPase in Golgi, confers salt tolerance in Saccharomyces cerevisiae by
inducing expression of PMR2, an Na(+)-ATPase in plasma membrane.
J Biol Chem.
276: 28694-28699

?