원예생명과학과

Lee M.R., Kim J.E., Choi J.Y., Park J.J., Kim H.R., Song B.R., Choi Young-Whan, Kim K.M., Song H. and Hwang D.Y. 2019 Anti-obesity effect in high-fat-diet-induced obese C57BL/6 mice: Study of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris EXPERIMENTAL AND THERAPEUTIC MEDICINE 17(3):2185 ~ 2193

 

Guo L., Li K., Cui Z.W., Kang J.S. , Son B.G. and Choi Young-Whan 2019 S-Petasin isolated from: Petasites japonicus exerts anti-adipogenic activity in the 3T3-L1 cell line by inhibiting PPAR-γ pathway signaling FOOD & FUNCTION 10(7):4396 ~ 4406

 

Park S.Y., Choi M.H., Li M., Li K., Park G. and Choi Young-Whan 2018 AMPK/Nrf2 signaling is involved in the anti-neuroinflarnmatory action of Petatewalide B from Petasites japonicus against lipopolysaccharides in microglia IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 40(3):232 ~ 241

 

Cho B.H., Jung Y.H., Kim D.J., Woo B.H., Jung J.E., Lee J.H., Choi Young-Whan, Park H.R. 2018 Acetylshikonin suppresses invasion of Porphyromonas gingivalis-infected YD10B oral cancer cells by modulating the interleukin-8/matrix metalloproteinase axis MOLECULAR MEDICINE REPORTS 17(2):2327 ~ 2334

 

Park S.Y., Choi M.H., Park G. and Choi Young-Whan 2018 Petasites japonicus bakkenolide B inhibits lipopolysaccharide-induced pro-inflammatory cytokines via AMPK/Nrf2 induction in microglia INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 41(3):1683 ~ 1692

 

Park S.Y., Choi Young-Whan(CA) and Park G. 2018 Nrf2-mediated neuroprotection against oxygen-glucose deprivation/reperfusion injury by emodin via AMPK-dependent inhibition of GSK-3 beta JOURNAL OF PHARMACY AND PHARMACOLOGY 70(4):525 ~ 535

 

Ye B.H., Kim E.J., Baek S.E., Choi Young-Whan, Park S.Y. and Kim C.D. 2018 α-Isocubebene modulates vascular tone by inhibiting myosin light chain phosphorylation in murine thoracic aorta The Korean Journal of Physiology & Pharmacology 22(4):437 ~ 445

 

Lee M.R., Kim J.E., Choi J.Y., Park J.J., Kim H.R., Song B.R., Park J.W., Kang M.J., Choi Young-Whan, Kim K.M. and Hwang D.Y. 2018 Morusin Functions as a Lipogenesis Inhibitor as Well as a Lipolysis Stimulator in Differentiated 3T3-L1 and Primary Adipocytes MOLECULES 23(8):0 ~ 0

 

Kim J.E., Lee M.R., Park J.J., Choi J.Y., Song B.R., Son H.J., Choi Young-Whan, Kim K.M., Hong J.T. and Hwang D.Y. 2018 Quercetin promotes gastrointestinal motility and mucin secretion in loperamide-induced constipation of SD rats through regulation of the mAChRs downstream signal PHARMACEUTICAL BIOLOGY 56(1):309 ~ 317

 

Kaowinn S., Kaewpiboon C., Kim J.E., Lee M.R., Hwang D.Y., Choi Young-Whan, Kim H.W., Park J.K., Song K.M., Lee N.H., Maeng J.S. and Chung Y.H. 2018 N-Benzyl-N-methyl-dodecan-1-amine, a novel compound from garlic, exerts anti-cancer effects on human A549 lung cancer cells overexpressing cancer upregulated gene (CUG)2 EUROPEAN JOURNAL OF PHARMACOLOGY 841():19 ~ 27

 

Jang M.A., Lee S.J., Baek S.E., Park S.Y., Choi Young-Whan and Kim C.D. 2017 α-Iso-Cubebene inhibits PDGF-induced vascular smooth muscle cell proliferation by suppressing osteopontin expression PLOS ONE 12(1):e0170699 ~ e0170699

 

Kim, J.E., Koh, E.K., Song, S.H., Sung, J.E. Lee, H.A. Lee, H.G. Choi, Y.W. and Hwang, D.Y. 2017 Effects of five candidate laxatives derived from Liriope platyphylla on the 5-HT receptor signaling pathway in three cell types present in the transverse colon MOLECULAR MEDICINE REPORTS 15(1):431 ~ 441

 

Song S.H., Choi S.M., Kim J.E., Lee H.A., Choi Y.H., Bae C.J., Choi Young-Whan(CA) and Hwang D.Y 2017 alpha-Isocubebenol alleviates scopolamine-induced cognitive impairment by repressing acetylcholinesterase activity NEUROSCIENCE LETTERS 638():121 ~ 128

 

Lee S.Y., Ahn S.M., Wang Z., Choi Young-Whan, Shin H.K. and Choi B.T. 2017 Neuroprotective effects of 2,3,5,4′-tetrahydoxystilbene-2-O-β-D-glucoside from Polygonum multiflorum against glutamate-induced oxidative toxicity in HT22 cells JOURNAL OF ETHNOPHARMACOLOGY 195():64 ~ 70

 

Hong S.H., Li M., Jeung E.B., Lee G.S., Hong E.J., Choi Young-Whan(CA) and An B.S.. 2017 Therapeutic effects of Schisandra chinensis on the hyperprolactinemia in rat INTERNATIONAL JOURNAL OF ONCOLOGY 50(4):1448 ~ 1454

 

Park S.Y., Jin M.L., Kang N.J., Park G. and Choi Young-Whan 2017 Anti-inflammatory effects of novel polygonum multiflorum compound via inhibiting NF-kappa B/MAPK and upregulating the Nrf2 pathways in LPS-stimulated microglia NEUROSCIENCE LETTERS 651():43 ~ 51

 

Jeong J.W., Kim J., Choi E.O., Kwon D.H., Kong G.M., Choi I.W., Kim B.H., Kim G.Y., Lee K.W., Kim K.Y., Kim S.G., Choi Young-Whan, Hong S.H., Park C. and Choi Y.H. 2017 SCHISANDRAE FRUCTUS ETHANOL EXTRACT AMELIORATES INFLAMMATORY RESPONSES AND ARTICULAR CARTILAGE DAMAGE IN MONOSODIUM IODOACETATE-INDUCED OSTEOARTHRITIS IN RATS Excli Journal 16():265 ~ 277

 

Jung J.M., Kim J.Y., Jin B.K., Choi Y.M., Hong C.O., Lee. H.H. Choi Young-Whan, Kang J.S. and Park Y.H. 2017 Characterization of the Lsi1 Homologs in Cucurbita moschata and C. ficifolia for Breeding of Stock Cultivars Used for Bloomless Cucumber Production Horticultural Science & Technology 35(3):333 ~ 343

 

Ko M.J., Jayaramaiah R., Gupta R., Kim S.W., An J.W., Wang Z. Li M., Kang N.J., Hong K.P., Kang J.S., Kim S.T. and Choi Young-Whan 2017 Evaluation of Bioactive Compounds in Strawberry Fruits by a Targeted Metabolomic Approach Horticultural Science & Technology 35(6):805 ~ 819

 

Jin-Woo Jeong, Hye Hyeon Lee, Ki Won Lee, Ki Young Kim, Sung Goo Kim, Su Hyun Hong, Gi-Young Kim, Cheol Park, Ho Kyoung Kim, Young Whan Choi and Yung Hyun CHOi. 2016. Mori folium inhibits interleukin-1β-induced expression of matrix metalloproteinases and inflammatory mediators by suppressing the activation of NF-κB andp38 MAPK in SW1353 human chondrocytes. International Journal of Molecular Medicine 37: 452 - 460, 2016

 

Young-Whan Choi, Kyoung-Pil Lee, Jung-Min Kim, Saeromi Kang, Soo-Jin Park, Jung-Min Lee, Hyung Ryong Moon, Jee H Jung, Young-Geun Lee, Dong-Soon Im. 2016. Petatewalide B, a novel compound from Petasites japonicus with anti-allergic activity. J Ethnopharmacol 178:17-24

 

Hee Ra Park, Ju Yeon Kim, Yujeong Lee, Hye Jeong Chun, Young Whan Choi, Hwa Kyoung Shin, Byung Tae Choi, Cheol Min Kim, Jaewon Lee. 2016. PMC-12, a traditional herbal medicine, enhances learning memory and hippocampal neurogenesis in mice. Neurosci Lett 23;617:254-63.

Ahn S.M., Kim H.N., Kim Y.R., Choi Young-Whan, Kim C.M., Shin H.K. and Choi B.T. 2016 Emodin from Polygonum multiflorum ameliorates oxidative toxicity in HT22 cells and deficits in photothrombotic ischemia JOURNAL OF ETHNOPHARMACOLOGY 188():13 ~ 20

 

Park S.Y, Jin M.L., Cha S.Y., Ko M.J., Choi Y.H., Park G.T. and Choi Young-Whan 2016 Novel compound from Polygonum multiflorum inhibits inflammatory response in LPS-stimulated microglia by upregulating AMPK/Nrf2 pathways NEUROCHEMISTRY INTERNATIONAL 100():21 ~ 29

 

Yoon H.K., An H.K., Ko M.J., Kim K.S., Mun S.W., Kim D.H., Kim C.M., Kim C.H., Choi Young-Whan(CA) and Lee Y.C. 2016 Upregulation of human ST8Sia VI (α2,8-sialyltransferase) gene expression by physcion in SK-N-BE(2)-C human neuroblastoma cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 17(8):1 ~ 13

 

Kim D.J., Lee J.H., Park H.R., Choi Young-Whan 2016 Acetylshikonin inhibits growth of oral squamous cell carcinoma by inducing apoptosis ARCHIVES OF ORAL BIOLOGY 70():149 ~ 157

 

Park S.Y., Jin M.L., Wang Z., Park G.T. and Choi Young-Whan 2016 2,3,4,5-tetrahydroxystilbene-2-O-beta-D-glucoside exerts anti-inflammatory effects on lipopolysaccharide-stimulated microglia by inhibiting NF-kappa B and activating AMPK/Nrf2 pathways FOOD AND CHEMICAL TOXICOLOGY 97():159 ~ 167

 

Park S.Y., Jin M.L., Ko M.J., Park G. and Choi Young-Whan. 2016 Anti-neuroinflammatory Effect of Emodin in LPS-Stimulated Microglia: Involvement of AMPK/Nrf2 Activation NEUROCHEMICAL RESEARCH 41(11):2981 ~ 2992

Kyoung-Pil Lee, Saeromi Kang, Min-Soo Noh, Soo-Jin Park, Jung-Min Kim, Hae Young Chung, Nam Kyung Je, Young-Geun Lee, Young-Whan Choi, and Dong-Soon Im. 2015. Therapeutic Effects of S-Petasin on Disease Models of Asthma and Peritonitis. Biomol Ther 23(1), 45-52

 

Shin-Ji Park, Mei Ling Jin, Hyun-Kyu An, Kyoung-Sook Kim, Min Jung Ko, Cheol Min Kim, Young Whan Choi (Corresponding author), Young-Choon Lee (Corresponding author). 2015. 1. 3. Emodin induces neurite outgrowth through PI3 K/Akt/GSK-3β-mediated signaling pathways in Neuro2a cells. Neuroscience Letters 588C : 101-107.

 

Sun Young Park, Won Jung Jung, Jum Soon Kang, Cheol-Min Kim, Geuntae Park, and Young-Whan Choi (Corresponding author). 2015. Neuroprotective effects of α-iso-cubebene against glutamate-induced damage in the HT22 hippocampal neuronal cell line. International Journal of Molecular Medicine 35(2): 525-532.

 

Chunja Nam, Jae-Sik Hwang, Myoung-Jun Kim, Young Whan Choi, Kyoung-Goo Han, Jong-Koo Kang. 2015. Single- and Repeat-dose Oral Toxicity Studies of Lithospermum erythrorhizon Extract in Dogs. Toxicological Research 31(1):77-88.

 

Byeong Hyeok Ye, Seung Jin Lee, Young Whan Choi, So Youn Park and Chi Dae Kim. 2015. Preventive effect of gomisin J from Schisandra chinensis on angiotensin II-induced hypertension via an increased nitric oxide bioavailability. Hypertens Res 38(3):169-77.

 

Hyung Bum Seo, Bo Kyung Kang, Ji Hyun Kim, Young Whan Choi, Jin Woo Hong, Byung Tae Choi, Hwa Kyoung Shin. 2015 May 27. Partially purified components of Uncaria sinensis attenuate blood brain barrier disruption after ischemic brain injury in mice. BMC Complement Altern Med 2015 27: 15:157.

 

Min Young Park, Yeon Suk Jung, Jung Hwa Park, Young Whan Choi, Jaewon Lee, Cheol Min Kim, Jin Ung Baek, Byung Tae Choi, and Hwa Kyoung Shin. 2015. PMC-12, a Prescription of Traditional Korean Medicine, Improves Amyloid β-Induced Cognitive Deficits through Modulation of Neuroinflammation. Evidence-Based Complementary and Alternative Medicine. 2015. 1-10.

 

Sung Min Ahn, Yu Ri Kim, Ha Neui Kim, Young Whan Choi, Jae Won Lee, Cheol Min Kim, Jin Ung Baek, Hwa Kyoung Shin, Byung Tae Choi. 2015. Neuroprotection and spatial memory enhancement of four herbal mixture extract in HT22 hippocampal cells and a mouse model of focal cerebral ischemia. BMC Complement Altern Med 5:202.

 

Minsoo Kook, Sung Kyun Lee, Sang Doo Kim, Ha Young Lee, Jae Sam Hwang, Young Whan Choi (Corresponding authors. Young Whan Choi (Corresponding author), and Yoe-Sik Bae. 2015. Anti-septic activity of α-cubebenoate isolated from Schisandra chinensis. BMB Rep 48(6):336-341

 

Sung Kyun Lee, Yoo Jung Park, Min Jung Ko, Ziyu Wang, Ha Young Lee, Young Whan Choi (Corresponding author), and Yoe-Sik Bae. 2015. A novel natural compound from garlic (Allium sativum L.) with therapeutic effects against experimental polymicrobial sepsis. Biochemical and Biophysical Research Communications 464 : 774-779.

 

Sun Young Park, Yung Hyun Choi, Geuntae Park, Young-Whan Choi (Corresponding author). 2015. 9. Neuroprotective effects of α-iso-cubebenol on glutamate-induced neurotoxicity. Environ Toxicol Pharmacol 40(2):549-56

 

Kyoung-Pil Lee, Saeromi Kang, Soo-Jin Park, Jung-Min Kim, Jung-Min Lee, Ae-Yeon Lee, Hae-Young Chung, Young-Whan Choi, Young-Geun Lee, Dong-Soon Im. 2015. 9. Anti-allergic effect of α-cubebenoate isolated from Schisandra chinensis using in vivo and in vitro experiments. J Ethnopharmacol 4;173:361-9.

 

Bo Kyung Kang, Mi Kyoung Kim, So Young Kim, Seung Jin Lee, Young Whan Choi, Byung Tae Choi, Hwa Kyoung Shin. 2015. 10. Anti-Neuroinflammatory Effects of Uncaria sinensis in LPS-Stimulated BV2 Microglia Cells and Focal Cerebral Ischemic Mice. Am J Chin Med 43(6):1099-115.

 

Chung-Tack Han, Myoung-Jun Kim, Seol-Hee Moon, Yu-Rim Jeon, Jae-Sik Hwang, Chunja Nam, Chong-Woo Park, Sun-Ho Lee, Jae-Bum Na, Chan-Sung Park, Hee-Won Park, Jung-Min Lee, Ho-Song Jang, Sun-Hee Park, Kyoung-Goo Han, Young Whan Choi, Hye-Yeong Lee, Jong-Koo Kang. 2015. 12. Acute and 28-Day Subacute Toxicity Studies of Hexane Extracts of the Roots of Lithospermum erythrorhizon in Sprague-Dawley Rats. Toxicol Res 31(4):403-14

 

Jin-Woo Jeong, Hye Hyeon Lee, Eun-Ok Choi, Ki Won Lee, Ki Young Kim, Sung Goo Kim, Su Hyun Hong, Gi-Young Kim, Cheol Park, Ho Kyoung Kim, Young Whan Choi, and Yung Hyun Choi. 2015. 10. Schisandrae Fructus Inhibits IL-1β-Induced Matrix Metalloproteinases and Inflammatory Mediators Production in SW1353 Human Chondrocytes by Suppressing NF-κB and MAPK Activation. Hypertens Res 38(3):169-77.

Sun Young Park, Tae Gyeong Park, Sang-Joon Lee, Yoe-Sik Bae, Min J. Ko and Young-Whan Choi (Corresponding author). 2014. α-Iso-cubebenol inhibits inflammation-mediated neurotoxicity and amyloid beta 1-42 fibril-induced microglial activation. Journal of Pharmacy and Pharmacology 66(1), 93-105

 

Ji Yeon Jang, Young Whan Choi (These authors contributed equally to this work), Ha Neui Kim, Yu Ri Kim, Jin Woo Hong, Dong Won Bae, Se Jin Park, Hwa Kyoung Shin, Byung Tae Choi. 2014. Neuroprotective effects of a novel single compound 1-Methoxyoctadecan-1-ol isolated from Uncaria sinensis in primary cortical neurons and a photothrombotic ischemia model. PLOS one. 9(1) : e85322.

 

Sun Young Park, Yoe-Sik Bae, Min Jung Ko, Sang-Joon Lee and Young-Whan Choi (Corresponding author). 2014. Comparison of anti-inflammatory potential of four different dibenzocyclooctadiene lignans in microglia; action via activation of PKA and Nrf-2 signaling and inhibition of MAPK/STAT/NF-κB pathways. Molecular Nutrition & Food Research Mol. Nutr. Food Res. 58, 738-748.

 

Soo Vin Lee, Kyung Ha Choi, Young Whan Choi, Jin Woo Hong, Jin Ung Back, Byung Tae Choi and Hwa Kyoung Shin. 2014. Hexane extracts of Polygonum multiflorum improve tissue and functional outcome following focal cerebral ischemia in mice. Molecular Medicine Reports 9: 1415-1421,

 

Sun Young Park, Rajasekar Seetharaman, Min Jung Ko, Do Yeon Kim, Tae Hoon Kim, Moo Kyoung Yoon, Jung Ho Kwak, Sang Joon Lee, Yoe Sik Bae, Young Whan Choi (Corresponding author). 2014. Ethyl linoleate from garlic attenuates lipopolysaccharide-induced pro-inflammatory cytokine production by inducing heme oxygenase-1 in RAW264.7 cells. International Immunopharmacology 19(2) 253-261.

 

Saeromi Kang, Kyoung-Pil Lee, Soo-Jin Park, Dae-Young Noh, Jung-Min Kim, Hyung Ryong Moon, Young-Geun Lee, Young-Whan Choi (Corresponding author), Dong-Soon Im. 2014. Identification of a novel anti-inflammatory compound, α-cubebenoate from Schisandra chinensis. Journal of Ethnopharmacology 153(2014) 242-249.

 

Nagaiya Ravichandran, Gopal Suresh, Balasubramanian Ramesh, Ramar Manikandan, Young Whan Choi, and Ganesan Vijaiyan Siva. 2014. Fisetin modulates mitochondrial enzymes and apoptotic signals in benzo(a)pyrene-induced lung cancer. Mol Cell Biochem (2014) 390:225-234. Mol Cell Biochem. 390(1-2):225-34.

 

Cheol Park, Sejin Park, Yoon Ho Chung, Gi-Young Kim, Young Whan Choi, Byung Woo Kim and Yung Hyun Choi. 2014. Induction of apoptosis by a hexane extract of aged black garlic inthe human leukemic U937 cells. Nutrition Research and Practice 2014;8(2):132-137.

 

Rajasekar Seetharaman, Sun Young Park, Moo Kyoung Yoon, Jung Ho Kwak, Beung Gu Son,Young Hoon Park, Jum Soon Kang, Young Jae Lee, Yung Hyun Choi, Yoe Sik Bae, and Young Whan Choi (Corresponding author). 2014. Heme Oxygenase-1-mediated anti-inflammatory effect of a novel garlic compound in RAW264.7 murine macrophages. Hort. Environ. Biotechnol. 55(2):148-157.

 

Jeong Moon, Sang Seok Koh, Waraporn Malilas, Il-Rae Cho, Chutima Kaewpiboon, Sirichat Kaowinn, Keesook Lee, Byung Hak Jhun, Young Whan Choi, Young-Hwa Chung. 2014. Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress. Eur J Pharmacol 2014 Jul 24;735:132-40.

 

Sun Young Park, Beung Gu Son, Young Hoon Park, Cheol-Min Kim, Geuntae Park, and Young-Whan Choi (Corresponding author). 2014. The neuroprotective effects of a-iso-cubebene on dopaminergic cell death: Involvement of CREB/Nrf2 signaling. Neurochemical Research 39:1759-1766

 

Ye Jin Han, Ju Hui Je, So Hyoung Kim, Sung Min Ahn, Ha Neui Kim, Yu Ri Kim, Young Whan Choi, Hwa Kyoung Shin, and Byung Tae Choi. 2014. Gastrodia elata shows neuroprotective effects via activation of PI3K signaling against oxidative glutamate toxicity in HT22 cells. The American Journal of Chinese Medicine 42(4): 1007-1019.

 

Sun Young Park, Do Yeon Kim, Jong-koo Kang, Geuntae Park, Young-Whan Choi (Corresponding author). 2014. Involvement of activation of the Nrf2/ARE pathway in protection against 6-OHDA-induced SH-SY5Y cell death by a-iso-cubebenol. NeuroToxicology 44, 160-168.

 

Young-Soon Kang, Min-Ho Han, Su-Hyun Hong, Cheol Park, Hye-Jin Hwang, Byung Woo Kim, Kim Ho Kyoung, Young Whan Choi, Cheol Min Kim, Yung Hyun Choi. 2014. Anti-inflammatory effects of Schisandra chinensis (Turcz.) Baill fruit through the inactivation of Nuclear Factor-κB and Mitogen-activated Protein Kinases signaling pathways in lipopolysaccharide stimulated Murine Macrophages. Journal of Cancer Prevention 19(4) 279-287.

Ji Yeon Jang, Ha Neui Kim, Yu Ri Kim, Young Whan Choi, Yung Hyun Choi, Jun Hyuk Lee, Hwa Kyoung Shin, Byung Tae Choi. 2013. Hexane extract from Polygonum multiflorum attenuates glutamate-induced apoptosis in primary cultured cortical neurons. Journal of Ethnopharmacology 145 (2013) 261-268. J Ethnopharmacol. 145(1):261-8.

 

Young Su Jung, Sung Kyun Lee, Chang Youp Ok, Eun Jung Cho, Joon Seong Park, Young Whan Choi (Corresponding authors), and Yoe-Sik Bae. 2013. Role of CXCR2 on the immune modulating activity of α-iso-cubebenol a natural compound isolated from the Schisandra chinensis fruit. Biochemical and Biophysical Research Communications 431 (3) (2013) 433-436

 

In Sik Hwang, Jee Eun Kim, Yong Ju Lee, Moon Hwa Kwak, Young Hwan Choi, Byeong Cheol Kang, Jin Tae Hong and Dae Youn Hwang. 2013. Protective effects of gomisin A isolated from Schisandra chinensis against CCl4-induced hepatic and renal injury. International Journal of Molecular Medicine 31: 888-898,

 

Ki-Hyung Kim, Jin Kyeong Park, Young-Whan Choi, Youn-Han Kim, Eun Na Lee, Ja-Rang Lee, Heui-Soo Kim, Sun-Yong Baek, Bong-Seon Kim, Kyu-Sup Lee, Sik Yoon .2013. Hexane extract of aged black garlic reduces cell proliferation and attenuates the expression of ICAM-1 and VCAM-1 in TNF-α-activated human endometrial stromal cells. International Journal of Molecular Medicine 32(1):67-78.

 

Kyoung-Pil Lee, Saeromi Kang, Soo-Jin Park, Young-Whan Choi, Young-Geun Lee, Dong-Soon Im. 2013. Anti-allergic and anti-inflammatory effects of bakkenolide B isolated from Petasites japonicus leaves. Journal of Ethnopharmacology 148 (2013): 890-894.

 

So Ra Kim, Yu Ri Jung, Hye Jin An, Dae Hyun Kim, Eun Ji Jang, Yeon Ja Choi, Kyoung Mi Moon, Min Hi Park, Chan Hum Park, Ki Wung Chung, Ha Ram Bae, Yung Whan Choi, Nam Deuk Kim, Hae Young Chung. 2013. Anti-Wrinkle and Anti-Inflammatory Effects of Active Garlic Components and the Inhibition of MMPs via NF-κB Signaling. PLoS One. 2013 Sep 16;8(9):e73877

 

Sun Young Park, Se Jin Park, Tae Gyeong Park, Seetharaman Rajasekar, Sang-Joon Lee, Young-Whan Choi (Corresponding author). 2013. Schizandrin C exerts anti-neuroinflammatory effects by upregulating phase II 2 detoxifying/antioxidant enzymes in microglia, International Immunopharmacology 17 (2013) 415-426

 

Sun Young Park, Se Jin Park, Nan Jeong Park, Woo Hong Joo, Sang-Joon Lee, and Young-Whan Choi (Corresponding author). 2013. α-iso-cubebene exerts neuroprotective effects in amyloid beta stimulated microglia activation. Neuroscience Letters. 143-148.

 

Ha Neui Kim, Yu Ri Kim, Ji Yeon Jang, Young Whan Choi, Jin Ung Baek, Jin Woo Hong, Yung Hyun Choi, Hwa Kyoung Shin, and Byung Tae Choi. 2013. Neuroprotective effects of Polygonum multiflorum extract against glutamate-induced oxidative toxicity in HT22 hippocampal cells. Journal of Ethnopharmacology 150(1), 108-115.

Hye-Jung Choi, Sang Myeong Lee, Sun-Hee Kim, Dong Wan Kim, Young Whnn Choi, and Woo Hong Joo. 2012. A novel Hericosporium isolate and its antimicrobial and cytotoxic pigment. J. Microbiol Biotech. (Journal of Microbiology and Biotechnology)22(9), 1214-1217.

 

Hye-Jung Choi, Dong Wan Kim, Young Whan Choi, Young Guen Lee, Yong-Ill Lee, Yong Kee Jeong and Woo Hong Joo. 2012. Broad-spectrum in vitro antimicrobial activities of Streptomyce ssp. strain BCNU 1001. Biotechnology and Bioprocess Engineering. 17: 576-583

 

Jieun Kim, Sun Guen Kim, Jun Sue Goo, Da Jeong Park, You Jin Lee, Iin Sik Hwang, Hae Ryeon Lee, Sun Il Choi, Young Ju Lee, Chung Hun Oh, Young Whan Choi (Corresponding author) and Dae Youn Hwang. 2012. The α-iso-cubebenol compound isolated from Schisandra chinensis induces p53-independent pathway-mediated apoptosis in hepatocellular carcinoma cells. ONCOLOGY REPORTS 28 (3): 1103-1109,

 

Il-Rae Cho, Sang Seok Koh, Waraporn Malilas, Ratakorn Srisuttee, Jeong Moon, Young-Whan Choi, Yoshiyuki Horio, Sangtaek Oh, Young-Hwa Chung. 2012. SIRT1 inhibits proliferation of pancreatic cancer cells expressing pancreatic adenocarcinoma up-regulated factor (PAUF), a novel oncogene, by suppression of β-catenin. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 423(2): 270-275,

 

Ji Young Park, Young Whan Choi, Jung Wook Yun, Jin Ung Bae, Kyo Won Seo, Seung Jin Lee, So Youn Park, Chi Dae Kim. 2012. Gomisin J from Schisandra chinensis induces vascular relaxation via activation of endothelial nitric oxide synthase. Vascular Pharmacology 57 : 124-130.

 

Ji Young Park, Jung Wook Yun, Young Whan Choi, Jin Ung Bae, Kyo Won Seo, Seung Jin Lee, So Youn Park, Ki Whan Hong, Chi Dae Kim. 2012. Antihypertensive effect of gomisin A from Schisandra chinensis on angiotensin II-induced hypertension via preservation of nitric oxide bioavailability. Hypertension Research 35(9): 928-934.

 

Sung Kyun Lee, Sang Doo Kim, Ha Young Lee, Suk-Hwan Baek, Min Jung Ko, Beung Gu Son, Sejin Park, Young Whan Choi (Corresponding authors), and Yoe-Sik Bae. 2012. α-Iso-cubebene, a natural compound isolated from Schisandra chinensis fruit, has therapeutic benefit against polymicrobial sepsis. Biochemical and Biophysical Research Communications. 416: 226-231.

 

Hye Jeong Kim, Min Ho Han, Gi Young Kim, Young-Whan Choi, and Yung Hyun Choi. 2012. Hexane extracts of garlic cloves induce apoptosis through the generation of reactive oxygen species in Hep3B human hepatocarcinoma cells. Oncology Reports 28: 1757-1763.

 

Ji-Yeon Jang, Ha-Neui Kim, Yu-Ri Kim, Jin-Woo Hong, Young-Whan Choi, Yung-Hyun Choi, Hwa-Kyoung Shin and Byung-Tae Choi. 2012. Hexane extract from Uncaria sinensis exhibits anti-apoptotic properties against glutamate-induced neurotoxicity in primary cultured cortical neurons. International Journal of Molecular Medicine 30: 1465-1472.

 

Sung Kyun Lee, Sang Doo Kim, Minsoo Kook, Ha Young Lee, Joon Seong Park, Young Hoon Park, Jum Soon Kang, Won Jung Jung, Young Whan Choi (Corresponding authors), and Yoe-Sik Bae. 2012. Therapeutic effects of α-iso-cubebenol, a natural compound isolated from the Schisandra chinensis fruit, against sepsis. Biochemical and biophysical research communications, 427(3):547-552.

 

Seetharaman Rajasekar, Da Jung Park, Cheol Park, Sejin Park, Young Hoon Park, Sun Tae Kim, Yung Hyun Choi, Young Whan Choi (Corresponding authors). 2012. In vitro and in vivo anticancer effects of Lithospermum erythrorhizon extract on B16F10 murine melanoma. Journal of Ethnopharmacology, 144: 335-345.

Eun Na Lee, Young Whan Choi (equally contributed to this paper), Hye Kyung Kim, Jin Kyeong Park, Hyo Jin Kim, Myoung June Kim, Hee Woo Lee, Ki-Hyung Kim, Sun Sik Bae, Bong Seon Kim, Sik Yoon. 2011. Chloroform extract of aged black garlic attenuates TNF-induced ROS generation, VCAM-1 expression, NF-B activation and adhesiveness for monocytes in human umbilical vein endothelial cells. Phytotherapy Research. 25: 92-100.

 

Young Mi Seok, Young Whan Choi (Young Mi Seok and Young Whan Choi equally contributed to this paper), Gyung-Duck Kim, Hye Young Kim, Yoh Takuwa and In Kyeom Kim. 2011. Effects of gomisin A on vascular contraction in rat aortic rings. Naunyn-Schmied Arch Pharmacol (2011) 383:45-56.

 

YOEN KYUNG LEE, JI EUN KIM, SO HEE NAM, JUN SEO GOO, SUN IL CHOI, YOUNG HWAN CHOI, CHANG JUN BAE, JONG MIN WOO, JUNG SIK CHO and DAE YOUN HWANG. 2011. Differential regulation of the biosynthesis of glucose transporters by the PI3-K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 27: 319-327.

 

Hye Kyung Kim, Young-Whan Choi (Denotes co-first authors), Eun Na Lee, Jin Kyeong Park, Sun-Gun Kim, Da-Jung Park, Bong-Seon Kim, Young-Tak Lim and Sik Yoon. 2011. 5-Hydroxymethylfurfural from Black Garlic Extract Prevents TNFα-induced Monocytic Cell Adhesion to HUVECs by Suppression of Vascular Cell Adhesion Molecule-1 Expression, Reactive Oxygen Species Generation and NF-κB Activation. Phytother Res 25: 965-974.

 

Jae Woong Shim, Ha Young Lee, Sang Doo Kim, Hak Jung Kim, Suk-Hwan Baek, Joon Seong Park, Sun Gun Kim, Young-Whan Choi (Corresponding author), and Yoe-Sik Bae. 2011. Chloroform Extract of Garlic (Allium sativum) Stimulates Production of Superoxide Anion and CXCL8 in Human Neutrophils. Hort. Environ. Biotechnol. 52(2):218-223.

 

Hyun Soo Park, Gi-Young Kim, Il-Whan Choi, Nam Deuk Kim, Hye Jin Hwang, Young-Whan Choi, and Yung Hyun Choi. 2011. Inhibition of Matrix Metalloproteinase Activities and Tightening of Tight Junctions by Diallyl Disulfide in AGS Human Gastric Carcinoma Cells. Journal of Food Science 76(4): T105-T111.

 

Sun Young Park, Da Jung Park, Young Hun Kim, Young Hee Kim, Sun Gun Kim, Kwang Jae Shon, Young-Whan Choi (Corresponding author). and Sang-Joon Lee. 2011. Upregulation of heme oxygenase-1 via PI3K/Akt and Nrf-2 signaling pathways mediates the anti-inflammatory activity of Schisandrin in Porphyromonas gingivalis LPS-stimulated macrophages. Immunology Letters 139 (2011) 93-101.

 

Sun Young Park, Da Jung Park, Young Hun Kim, Young Hee Kim, Young-Whan Choi (Corresponding author) and Sang-Joon Lee. 2011. Schisandra chinensis α-iso-cubebenol induces heme oxygenase-1 expression through 2 PI3K/Akt and Nrf2 signaling and has anti-inflammatory activity in Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages. International Immunopharmacology 11, 1907-1915.

 

Young Mi Choi, In Soo Choi, Sang Mong Lee, Dae Youn Hwang, Young Whan Choi, Young Hoon Park. 2011. Transcriptome Analysis of the Effects of Gomisin A on the Recovery of Carbon Tetrachloride-Induced Damage in Rat Liver. Lab Anim Res 2011: 27(2), 161-169.

 

Sun Haeng Park, Ji Hyun Kim, Se Jin Park, Sun Sik Bae, Young Whan Choi, Jin Woo Hong, Byung Tae Choi, Hwa Kyoung Shin. 2011. Protective effect of hexane extracts of Uncaria sinensis against photothrombotic ischemic injury in mice. Journal of Ethnopharmacology 138 (3): 774-779.

 

Eun Yeon Ryu, Sun Young Park, Sun Gun Kim, Da Jung Park, Jum Soon Kang, Young Hun Kim, Rajaseker Seetharaman, Young-Whan Choi (correspondence), and Sang-Joon Lee. 2011. Anti-Inflammatory Effect of Heme Oxygenase-1 Toward Porphyromonas gingivalis Lipopolysaccharide in Macrophages Exposed to Gomisins A, G, and J. J Med Food 14 (12) 2011, 1519-1526

 

Ji Hyun Hwang, Seong Gyu Ahn, Ju Youl Oh, Young Whan Choi, Jum Soon Kang, Young Hoon Park. 2011. Functional characterization of watermelon (Citrullus lanatus L.) EST-SSR by gel electrophoresis and high resolution melting analysis. Scientia Horticulturae 130(4): 715-724.

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