제약 4.0 미래인재 양성 교육연구팀

Anti-Browning Effect of 2-Mercaptobenzo[d]imidazole Analogs with Antioxidant Activity on Freshly-Cut Apple Slices and Their Highly Potent Tyrosinase Inhibitory Activity. Antioxidants, MDPI, 2023-10

권 12 호 10 페이지 1814 ~ 1814

Identification and molecular mechanism of novel 5-alkenyl-2-benzylaminothiazol-4(5H)-one analogs as anti-melanogenic and antioxidant agents. BIOORGANIC CHEMISTRY, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2023-08

권 140 페이지 106763 ~ 106763

Anti-tyrosinase flavone derivatives and their anti-melanogenic activities: Importance of the ?-phenyl-?,?-unsaturated carbonyl scaffold. BIOORGANIC CHEMISTRY, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2023-06

권 135 페이지 106504 ~ 106504

Design, Synthesis, In Vitro, and In Silico Insights of 5-(Substituted benzylidene)-2-phenylthiazol-4(5H)-one Derivatives: A Novel Class of Anti-Melanogenic Compounds. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2023-04

권 28 호 8 페이지 3293 ~ 3293

Design and Synthesis of (Z)-2-(Benzylamino)-5-benzylidenethiazol-4(5H)-one Derivatives as Tyrosinase Inhibitors and Their Anti-Melanogenic and Antioxidant Effects. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2023-01

권 28 호 2 페이지 848 ~ 848

Discovery and optimization of novel 3-benzyl-N-phenyl-1H-pyrazole-5-carboxamides as bifunctional antidiabetic agents stimulating both insulin secretion and glucose uptake. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2021-05

권 217 페이지 113325 ~ 113339

(E)-1-(Furan-2-yl)-(substituted phenyl)prop-2-en-1-one Derivatives as Tyrosinase Inhibitors and Melanogenesis Inhibition: An In Vitro and In Silico Study. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2020-11

권 25 호 22 페이지 5460 ~ 5460

MHY2013 Modulates Age-related Inflammation and Insulin Resistance by Suppressing the Akt/FOXO1/IL-1β Axis and MAPK-mediated NF-κB Signaling in Aged Rat Liver. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, LIPPINCOTT WILLIAMS & WILKINS, 2020-09

권 28 호 8 페이지 579 ~ 592

A new sirt1 inhibitor, MHY2245, induces autophagy and inhibits energy metabolism via PKM2/MTOR pathway in human ovarian cancer cells. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, IVYSPRING INT PUBL, 2020-04

권 16 호 11 페이지 1901 ~ 1916

A new histone deacetylase inhibitor, MHY4381, induces apoptosis via generation of reactive oxygen species in human prostate cancer cells. BIOMOLECULES & THERAPEUTICS, KOREAN SOC APPLIED PHARMACOLOGY, 2020-03

권 28 호 2 페이지 184 ~ 194

PPARα/β activation alleviates age-associated renal fibrosis in sprague dawley rats. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, GERONTOLOGICAL SOCIETY AMER, 2020-02

권 75 호 3 페이지 452 ~ 458

Design of balanced COX inhibitors based on anti-inflammatory and/or COX-2 inhibitory ascidian metabolites. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2019-10

권 180 페이지 86 ~ 98

Pro-apoptotic effect of the novel benzylidene derivative MHY695 in human colon cancer cells. ONCOLOGY LETTERS, SPANDIDOS PUBL LTD, 2019-09

권 18 호 3 페이지 3256 ~ 3264

Inhibitory effects of N-(acryloyl)benzamide derivatives on tyrosinase and melanogenesis. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2019-09

권 27 호 17 페이지 3929 ~ 3937

In vitro and in silico insights into tyrosinase inhibitors with (E)-benzylidene-1-indanone derivatives. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, ELSEVIER , 2019-08

권 17 페이지 1255 ~ 1264

In vitro and in vivo evidence of tyrosinase inhibitory activity of a synthesized (Z)-5-(3-hydroxy-4-methoxybenzylidene)-2-thioxothiazolidin-4-one (5-HMT). EXPERIMENTAL DERMATOLOGY, BLACKWELL MUNKSGAARD, 2019-06

권 28 호 6 페이지 734 ~ 737

Antioxidant, anti-tyrosinase and anti-melanogenic effects of (E)-2,3-diphenylacrylic acid derivatives. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2019-06

권 27 호 11 페이지 2192 ~ 2200

Tyrosinase inhibition and anti-melanin generation effect of cinnamamide analogues. BIOORGANIC CHEMISTRY, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019-06

권 87 페이지 43 ~ 55

MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, LANDES BIOSCIENCE, 2019-05

권 1 호 0 페이지 1 ~ 19

Neuroprotective effects of MHY908, a PPAR α/γ dual agonist, in a MPTP-induced Parkinson's disease model. BRAIN RESEARCH, ELSEVIER SCIENCE BV, 2019-02

권 1704 페이지 47 ~ 58

The tyrosinase-inhibitory effects of 2-phenyl-1,4-naphthoquinone analogs: importance of the (E)--phenyl-,-unsaturated carbonyl scaffold of an endomethylene type. MEDICINAL CHEMISTRY RESEARCH, BIRKHAUSER BOSTON INC, 2019-01

권 28 호 1 페이지 95 ~ 103

Synthesis of cinnamic amide derivatives and their anti-melanogenic effect in alpha-MSH-stimulated B16F10 melanoma cells. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2019-01

권 161 페이지 78 ~ 92

Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-12

권 23 호 12 페이지 3307 ~ 3307

In vitro and in vivo evaluation of MHY908-loaded nanostructured lipid carriers for the topical treatment of hyperpigmentation. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, EDITIONS SANTE, 2018-12

권 48 페이지 457 ~ 465

Design, synthesis and anti-melanogenic effect of cinnamamide derivatives. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2018-11

권 26 호 21 페이지 5672 ~ 5681

A Potent Tyrosinase Inhibitor, (E)-3-(2,4-Dihydroxyphenyl)-1-(thiophen-2-yl)prop-2-en-1-one, with Anti-Melanogenesis Properties in alpha-MSH and IBMX-Induced B16F10 Melanoma Cells. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-10

권 23 호 10 페이지 2725 ~ 2725

Design of PPAR-gamma agonist based on algal metabolites and the endogenous ligand 15-deoxy-Delta(12,) (14)-prostaglandin J(2). EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2018-09

권 157 페이지 1192 ~ 1201

A new synthetic histone deacetylase inhibitor, MHY2256, induces apoptosis and autophagy cell death in endometrial cancer cells via p53 acetylation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-09

권 19 호 9 페이지 1 ~ 12

Novel β-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer. CELL DEATH & DISEASE, NATURE PUBLISHING GROUP, 2018-09

권 9 호 9 페이지 1 ~ 17

Hepatoprotective Effects of MHY3200 on High-Fat, Diet-Induced, Non-Alcoholic Fatty Liver Disease in Rats. MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2018-08

권 23 호 8 페이지 2057 ~ 2057

The tyrosinase inhibitory effects of isoxazolone derivatives with a (Z)-β-phenyl-α, β-unsaturated carbonyl scaffold. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2018-08

권 26 호 14 페이지 3882 ~ 3889

A novel synthetic compound, (Z)-5-(3-hydroxy-4-methoxybenzylidene)-2-iminothiazolidin-4-one (MHY773) inhibits mushroom tyrosinase. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, JAPAN SOC BIOSCI BIOTECHN AGROCHEM, 2018-05

권 82 호 5 페이지 759 ~ 767

Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2018-02

권 28 호 4 페이지 684 ~ 688

Colon-targeted delivery of cyclosporine A using dual-functional Eudragit (R) FS30D/PLGA nanoparticles ameliorates murine experimental colitis. INTERNATIONAL JOURNAL OF NANOMEDICINE, DOVE MEDICAL PRESS LTD, 2018-02

권 13 페이지 1225 ~ 1240

A PPAR Pan Agonist, MHY2013 Alleviates Age-Related Hepatic Lipid Accumulation by Promoting Fatty Acid Oxidation and Suppressing Inflammation. BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, 2018-01

권 41 호 1 페이지 29 ~ 35

Evaluation of Antimelanogenic Activity and Mechanism of Galangin in Silico and in Vivo. BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, 2018-01

권 41 호 1 페이지 73 ~ 79

Antibacterial activities of viriditoxin congeners and synthetic analogues against fish pathogens. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2017-11

권 27 호 22 페이지 4970 ~ 4974

Thio-barbiturate-derived compounds are novel antioxidants to prevent LPS-induced inflammation in the liver. ONCOTARGET, IMPACT JOURNALS LLC, 2017-10

권 8 호 53 페이지 91662 ~ 91673

2-(3, 4-dihydroxybenzylidene)malononitrile as a novel antimelanogenic compound. ONCOTARGET, IMPACT JOURNALS LLC, 2017-10

권 8 호 53 페이지 91481 ~ 91493

Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. ONCOTARGET, IMPACT JOURNALS LLC, 2017-07

권 8 호 28 페이지 46273 ~ 46285

PPAR alpha activation by MHY908 attenuates age-related renal inflammation through modulation of the ROS/Akt/Fox01 pathway. EXPERIMENTAL GERONTOLOGY, PERGAMON-ELSEVIER SCIENCE LTD, 2017-06

권 92 페이지 87 ~ 95

Design, synthesis, and antimelanogenic effects of (2-substituted phenyl-1,3-dithiolan-4-yl)methanol derivatives. DRUG DESIGN DEVELOPMENT AND THERAPY, Dove Medical Press, 2017-03

권 11 페이지 827 ~ 839

Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)- 2-methylpropanoic acid (MHY2013). ONCOTARGET, IMPACT JOURNALS LLC, 2017-03

권 8 호 10 페이지 16912 ~ 16924

벤조[b][1,4]옥사진-3(4H)-치온 유도체의 합성과 이들의 타이로시네이즈저해 활성. 약학회지, 대한약학회, 2017-02

권 61 호 1 페이지 6 ~ 11

Anticancer Effects of a New SIRT Inhibitor, MHY2256, against Human Breast Cancer MCF-7 Cells via Regulation of MDM2-p53 Binding. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, IVYSPRING INT PUBL, 2016-12

권 12 호 12 페이지 1555 ~ 1567

Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation. DRUG DESIGN DEVELOPMENT AND THERAPY, Dove Medical Press, 2016-12

권 10 페이지 3947 ~ 3957

4-(6,7-Dihydro-5H-indeno[5,6-d] thiazol-2-yl) benzene-1,3-diol prevents UV-induced melanogenesis and wrinkle formation in HRM-2 hairless mice. JOURNAL OF DERMATOLOGICAL SCIENCE, ELSEVIER SCI IRELAND LTD, 2016-11

권 84 호 2 페이지 213 ~ 216

Antimelanogenic activity of MHY384 via inhibition of NO-induced cGMP signalling. EXPERIMENTAL DERMATOLOGY, BLACKWELL MUNKSGAARD, 2016-08

권 25 호 8 페이지 652 ~ 654

(Z)-5-(2,4-Dihydroxybenzylidene)thiazolidine-2,4-dione Prevents UVB-Induced Melanogenesis and Wrinkle Formation through Suppressing Oxidative Stress in HRM-2 Hairless Mice. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, LANDES BIOSCIENCE, 2016-04

권 2016 호 2761463 페이지 1 ~ 9

Effects of MHY908, a New Synthetic PPAR alpha/gamma Dual Agonist, on Inflammatory Responses and Insulin Resistance in Aged Rats. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, GERONTOLOGICAL SOCIETY AMER, 2016-03

권 71 호 3 페이지 300 ~ 309

Tyrosinase inhibitors: A patent review (2011-2015). EXPERT OPINION ON THERAPEUTIC PATENTS, ASHLEY PUBLICATIONS LTD, 2016-03

권 26 호 3 페이지 347 ~ 362

Petatewalide B, a novel compound from Petasites japonicus with anti-allergic activity. JOURNAL OF ETHNOPHARMACOLOGY, ELSEVIER SCI IRELAND LTD, 2016-02

권 178 페이지 17 ~ 24

(E)-2-Cyano-3-(substituted phenyl)acrylamide analogs as potent inhibitors of tyrosinase: A linear β-phenyl-α,β-unsaturated carbonyl scaffold. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2015-12

권 23 호 24 페이지 7728 ~ 7734

Dimeric Octaketide Spiroketals from the Jellyfish-Derived Fungus Paecilomyces variotii J08NF-1. JOURNAL OF NATURAL PRODUCTS, AMER CHEMICAL SOC, 2015-11

권 78 호 11 페이지 2832 ~ 2836

Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces cell cycle arrest and apoptosis via the downregulation of Akt in human lung cancer cells. ONCOLOGY REPORTS, PROFESSOR D A SPANDIDOS, 2015-11

권 34 호 5 페이지 2431 ~ 2438

A Novel Peroxisome Proliferator-activated Receptor (PPAR)y Agonist 2-Hydroxyethyl 5-chloro-4, 5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis. JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2015-10

권 290 호 42 페이지 25609 ~ 25619

A New Histone Deacetylase Inhibitor, MHY219, Inhibits the Migration of Human Prostate Cancer Cells via HDAC1. BIOMOLECULES & THERAPEUTICS, KOREAN SOC APPLIED PHARMACOLOGY, 2015-09

권 23 호 5 페이지 434 ~ 441

(2R/S,4R)-2-(2,4-Dihydroxyphenyl)thiazolidine-4-carboxylic acid prevents UV-induced wrinkle formation through inhibiting NF-kappa B-mediated inflammation. JOURNAL OF DERMATOLOGICAL SCIENCE, ELSEVIER SCI IRELAND LTD, 2015-09

권 79 호 3 페이지 313 ~ 316

Design, synthesis, and anti-melanogenic effects of (E)-2-benzoyl-3-(substituted phenyl)acrylonitriles. DRUG DESIGN DEVELOPMENT AND THERAPY, Dove Medical Press, 2015-08

권 9 호 0 페이지 4259 ~ 4268

(Z)-2-(Benzo[d]thiazol-2-ylamino)-5-(substituted benzylidene)thiazol-4(5H)-one Derivatives as Novel Tyrosinase Inhibitors. BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, 2015-08

권 38 호 8 페이지 1227 ~ 1233

Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process. DRUG DESIGN DEVELOPMENT AND THERAPY, Dove Medical Press, 2015-08

권 9 페이지 4269 ~ 4277

Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-kappa B, an anti-inflammatory target. DRUG DESIGN DEVELOPMENT AND THERAPY, Dove Medical Press, 2015-08

권 9 페이지 4227 ~ 4237

MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY, PROFESSOR D A SPANDIDOS, 2015-08

권 47 호 2 페이지 563 ~ 572

Colon-targeted delivery of budesonide using dual pH- and time-dependent polymeric nanoparticles for colitis therapy. DRUG DESIGN DEVELOPMENT AND THERAPY, Dove Medical Press, 2015-07

권 9 호 0 페이지 3789 ~ 3799

Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles. INTERNATIONAL JOURNAL OF NANOMEDICINE, DOVE MEDICAL PRESS LTD, 2015-07

권 10 호 0 페이지 4565 ~ 4580

MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, mediates oxidative stress-induced apoptosis in AGS human gastric cancer cells. ONCOLOGY REPORTS, PROFESSOR D A SPANDIDOS, 2015-07

권 34 호 1 페이지 288 ~ 294

Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl) phenoxy]-2-methylpropanoic acid (MHY908). ARCHIVES OF PHARMACAL RESEARCH, 대한약학회, 2015-04

권 38 호 4 페이지 505 ~ 511

Highly Efficient Synthesis of Conformationally Fixed Bicyclo[3.1.0]hexyl Nucleosides with an Ethenyl Group at C3′-Position as Potential Antiviral Agents. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 대한화학회, 2014-09

권 35 호 9 페이지 2649 ~ 2654

Benzylidene-linked thiohydantoin derivatives as inhibitors of tyrosinase and melanogenesis: importance of the beta-phenyl-alpha,beta-unsaturated carbonyl functionality. MEDCHEMCOMM, ROYAL SOC CHEMISTRY, 2014-09

권 5 호 9 페이지 1410 ~ 1417

Chinese Prescription Kangen-karyu and Salviae Miltiorrhizae Radix Improve Age-Related Oxidative Stress and Inflammatory Response through the PI3K/Akt or MAPK Pathways. AMERICAN JOURNAL OF CHINESE MEDICINE, WORLD SCIENTIFIC PUBL CO PTE LTD, 2014-04

권 42 호 4 페이지 987 ~ 1005

Identification of a novel anti-inflammatory compound, α-cubebenoate from Schisandra chinensis. JOURNAL OF ETHNOPHARMACOLOGY, ELSEVIER SCI IRELAND LTD, 2014-04

권 153 호 1 페이지 242 ~ 249

MHY884, a newly synthesized tyrosinase inhibitor, suppresses UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2014-03

권 24 호 5 페이지 1344 ~ 1348

MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY, PROFESSOR D A SPANDIDOS, 2014-03

권 44 호 3 페이지 905 ~ 911

A novel oxiranylchromenone derivative, MHY336, inducesapoptosis and cell cycle arrest via a p53- and p21-dependent pathway in HCT116 human colon cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY, PROFESSOR D A SPANDIDOS, 2014-03

권 44 호 3 페이지 943 ~ 949

A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-κB in HCT116 human colon cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY, PROFESSOR D A SPANDIDOS, 2014-01

권 44 호 1 페이지 256 ~ 264

A novel anthracene derivative, MHY412, induces apoptosis in doxorubicin-resistant MCF-7/Adr human breast cancer cells through cell cycle arrest and downregulation of P-glycoprotein expression. INTERNATIONAL JOURNAL OF ONCOLOGY, PROFESSOR D A SPANDIDOS, 2014-01

권 44 호 1 페이지 167 ~ 176

Potent Anti-Diabetic Effects of MHY908, a Newly Synthesized PPAR alpha/gamma Dual Agonist in db/db Mice. PLOS ONE, PUBLIC LIBRARY SCIENCE, 2013-11

권 8 호 11 페이지 1 ~ 9

The Novel PPAR alpha/gamma Dual Agonist MHY 966 Modulates UVB-Induced Skin Inflammation by Inhibiting NF-kappa B Activity. PLOS ONE, PUBLIC LIBRARY SCIENCE, 2013-10

권 8 호 10 페이지 e76820 ~ e76820

Characterization of a small molecule inhibitor of melanogenesis that inhibits tyrosinase activity and scavenges nitric oxide (NO). BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, ELSEVIER SCIENCE BV, 2013-10

권 1830 페이지 4752 ~ 4761

Anti-melanogenic effect of (Z)-5-(2,4-dihydroxybenzylidene) thiazolidine-2,4-dione, a novel tyrosinase inhibitor. ARCHIVES OF PHARMACAL RESEARCH, 대한약학회, 2013-10

권 36 페이지 1189 ~ 1197

The inhibitory effect of a synthetic compound, (Z)-5-(2,4-dihydroxybenzylidene) thiazolidine-2,4-dione (MHY498), on nitric oxide-induced melanogenesis. BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2013-08

권 23 호 15 페이지 4332 ~ 4335

De novo tyrosinase inhibitor: 4-(6,7-Dihydro-5H-indeno[5,6-d]thiazol-2-yl) benzene-1,3-diol (MHY1556). BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2013-07

권 23 호 14 페이지 4172 ~ 4176

A novel histone deacetylase (HDAC) inhibitor MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells. BIOMEDICINE & PHARMACOTHERAPY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2013-06

권 67 호 5 페이지 407 ~ 415

Synthesis of Novel N-(2-Hydroxyphenyl)arylsulfonamides as Selective HDAC Inhibitory and Cytotoxic Agents. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 대한화학회, 2013-05

권 34 호 5 페이지 1487 ~ 1493

Development of Akt-activated GSK3 beta inhibitory peptide. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013-05

권 434 호 4 페이지 735 ~ 739

Molecular Docking Studies of (1E,3E,5E)-1,6-Bis(substituted phenyl)hexa-1,3,5-triene and 1,4-Bis(substituted trans-styryl)benzene Analogs as Novel Tyrosinase Inhibitors. BIOLOGICAL & PHARMACEUTICAL BULLETIN, PHARMACEUTICAL SOC JAPAN, 2013-01

권 36 페이지 55 ~ 65

A Novel Synthesized Tyrosinase Inhibitor: (E)-2-((2,4-Dihydroxyphenyl)diazenyl)phenyl 4-Methylbenzenesulfonate as an Azo-Resveratrol Analog. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, JAPAN SOC BIOSCI BIOTECHN AGROCHEM, 2013-01

권 77 페이지 65 ~ 72

Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces apoptosis and cell cycle arrest in HCT116 human colon cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY, PROFESSOR D A SPANDIDOS, 2012-12

권 41 호 6 페이지 2057 ~ 2064

Suppression of melanogenesis by a newly synthesized compound, MHY966 via the nitric oxide/protein kinase G signaling pathway in murine skin. JOURNAL OF DERMATOLOGICAL SCIENCE, ELSEVIER SCI IRELAND LTD, 2012-12

권 68 호 3 페이지 164 ~ 171

Synthesis of novel azo-resveratrol, azo-oxyresveratrol and their derivatives as potent tyrosinase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2012-12

권 22 호 24 페이지 7451 ~ 7455

A novel carbazole derivative, MHY407, sensitizes cancer cells to doxorubicin-, etoposide-, and radiation treatment via DNA damage. EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, 2012-12

권 697 호 1-3 페이지 24 ~ 31

Synthesis and Preliminary In Vitro Biological Evaluation of 5-Chloro-2-(Substituted Phenyl)Benzo[d]Thiazole Derivatives Designed As Novel Antimelanogenesis Agents. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, HUMANA PRESS INC, 2012-11

권 168 호 6 페이지 1416 ~ 1433

Design, synthesis, and evaluation of (E)-N-substituted benzylidene-aniline derivatives as tyrosinase inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2012-11

권 57 페이지 383 ~ 390

A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells. INVESTIGATIONAL NEW DRUGS, SPRINGER, 2012-10

권 30 호 5 페이지 1887 ~ 1898

새로운 사이클로프로필 뉴크레오사이드 유도체의 합성과 생리활성. 약학회지, 대한약학회, 2012-08

권 56 호 4 페이지 230 ~ 235

Pulmonary administered palmitic-acid modified exendin-4 peptide prolongs hypoglycemia in type 2 diabetic db/db mice. REGULATORY PEPTIDES, ELSEVIER SCIENCE BV, 2012-08

권 177 호 1-3 페이지 68 ~ 72

Inhibitory Effect of mTOR Activator MHY1485 on Autophagy: Suppression of Lysosomal Fusion. PLOS ONE, PUBLIC LIBRARY SCIENCE, 2012-08

권 7 호 8 페이지 1 ~ 10

In vitro stability and in vivo anti-inflammatory efficacy of synthetic jasmonates. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2012-07

권 20 호 13 페이지 4109 ~ 4116

Evaluation of in vitro and in vivo anti-melanogenic activity of a newly synthesized strong tyrosinase inhibitor (E)-3-(2,4 dihydroxybenzylidene)pyrrolidine-2,5-dione (3-DBP). BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, ELSEVIER SCIENCE BV, 2012-07

권 1820 호 7 페이지 962 ~ 969

Characterization of a novel tyrosinase inhibitor, (2RS,4R)-2-(2,4-dihydroxyphenyl) thiazolidine-4-carboxylic acid (MHY384). BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, ELSEVIER SCIENCE BV, 2012-04

권 1820 호 4 페이지 542 ~ 549

Design and synthesis of 5-(substituted benzylidene)thiazolidine-2,4-dione derivatives as novel tyrosinase inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2012-03

권 49 페이지 245 ~ 252

Preparation and evaluation of palmitic acid-conjugated exendin-4 with delayed absorption and prolonged circulation for longer hypoglycemia. INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER SCIENCE BV, 2012-03

권 424 호 1-2 페이지 50 ~ 57

Design, synthesis and biological evaluation of 2-(substituted phenyl)thiazolidine-4-carboxylic acid derivatives as novel tyrosinase inhibitors. Journal of Sensor Science and Technology, 한국센서학회, 2012-02

권 94 호 2 페이지 533 ~ 540

Stereoselective synthesis and anti-HCV activity of conformationally restricted 2′-C-substituted carbanucleosides. TETRAHEDRON, PERGAMON-ELSEVIER SCIENCE LTD, 2012-01

권 68 호 4 페이지 1253 ~ 1261

Crystallization and preliminary X-ray crystallographic analysis of the Β-N-acetylglucosaminidase CbsA from Thermotoga neapolitana. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, BLACKWELL PUBLISHING, 2012-01

권 68 호 1 페이지 56 ~ 58

Design, synthesis and anticancer activity of novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivatives. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2011-10

권 21 호 19 페이지 5730 ~ 5734

Synthesis of enantiomerically pure d- and l-bicyclo[3.1.0]hexenyl carbanucleosides and their antiviral evaluation. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2011-07

권 19 호 13 페이지 3945 ~ 3955

Synthesis and biological activity of hydroxybenzylidenyl pyrrolidine-2,5-dione derivatives as new potent inhibitors of tyrosinase. MEDCHEMCOMM, ROYAL SOC CHEMISTRY, 2011-06

권 2 호 6 페이지 542 ~ 549

Synthesis and Importance of Bulky Aromatic Cap of Novel SAHA Analogs for HDAC Inhibition and Anticancer Activity. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 대한화학회, 2011-06

권 32 호 6 페이지 1891 ~ 1896

Analogs of 5-(substituted benzylidene)hydantoin as inhibitors of tyrosinase and melanin formation. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, ELSEVIER SCIENCE BV, 2011-06

권 1810 호 6 페이지 612 ~ 619

Crystallization and preliminary X-ray crystallographic analysis of Salmonella Typhimurium CueP. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, BLACKWELL PUBLISHING, 2011-06

권 67 호 6 페이지 675 ~ 677

A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells. EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE BV, 2011-05

권 658 호 2-3 페이지 98 ~ 107

Synthesis and biological activity of hydroxy substituted phenyl-benzo[d]thiazole analogues for antityrosinase activity in B16 cells. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2011-04

권 21 호 8 페이지 2445 ~ 2449

Using conformationally locked nucleosides to calibrate the anomeric effect: implications for glycosyl bond stability. TETRAHEDRON, PERGAMON-ELSEVIER SCIENCE LTD, 2010-08

권 66 호 34 페이지 6707 ~ 6717

Anticancer effects of the MHY218 novel hydroxamic acid-derived histone deacetylase inhibitor in human ovarian cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY, PROFESSOR D A SPANDIDOS, 2010-08

권 37 호 2 페이지 419 ~ 428

First synthesis of 2 '-oxabicyclo[3.1.0]hexyl nucleosides with a north conformation. TETRAHEDRON, PERGAMON-ELSEVIER SCIENCE LTD, 2010-02

권 66 호 9 페이지 1706 ~ 1715

Highly Concise Synthesis of 3 '-Up-ethynyl-5 '-methylbicyclo[3.1.0]hexyl Purine and Pyrimidine Nucleoside Derivatives Using Rhodium(II) Carbenoid Cycloaddition and Highly Diastereoselective Grignard Reaction. CHINESE JOURNAL OF CHEMISTRY, SCIENCE CHINA PRESS, 2009-12

권 27 호 12 페이지 2405 ~ 2412

Design and synthesis of N-6-substituted-4 '-thioadenosine-5 '-uronamides as potent and selective human A(3) adenosine receptor agonists. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2009-12

권 17 호 23 페이지 8003 ~ 8011

Efficient and practical synthesis of L-hamamelose. CARBOHYDRATE RESEARCH, ELSEVIER SCI LTD, 2009-11

권 344 호 17 페이지 2317 ~ 2321

Synthesis of Neplanocin A Analog with 2 '-up-C-Methyl Substituent as Potential Anti-HCV Agent. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 대한화학회, 2009-09

권 30 호 9 페이지 2043 ~ 2050

Design, Synthesis, Antitumor Activity and Mode of Action of Novel Oxiranyl and Thiiranyl Phenol Derivatives. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 대한화학회, 2009-07

권 30 호 7 페이지 1463 ~ 1469

Design and Synthesis of 5 ''-Iodoneplanocin A and Its Analogues as Potential S-Adenosylhomocysteine Hydrolase Inhibitor. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 대한화학회, 2008-12

권 29 페이지 2487 ~ 2490

Synthesis of Methyl-substituted Bicyclic Carbanucleoside Analogs as Potential Antiherpetic Agents. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 대한화학회, 2008-10

권 29 페이지 1977 ~ 1982

Structure-Activity Relationships of Truncated D- and L-4 '-Thioadenosine Derivatives as Species-Independent A(3) Adenosine Receptor Antagonists. JOURNAL OF MEDICINAL CHEMISTRY, AMER CHEMICAL SOC, 2008-09

권 51 페이지 6609 ~ 6613

Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X(7) receptor. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2008-01

권 18 페이지 571 ~ 575

Design, synthesis, and anti-tumor activity of 4 '-thionucleosides as potent and selective agonists at the human A(3) adenosine receptor. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-10

권 26 페이지 1565 ~ 1568

Asymmetric synthesis and biological activity of L-bicyclocarba-d4T. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-10

권 26 페이지 1653 ~ 1657

Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active site of S-adenosylhomocysteine hydrolase. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2007-08

권 17 페이지 4456 ~ 4459

Asymmetric synthesis of cyclopropyl-fused 2'-C-methylcarbanucleosides as potential anti-HCV agents. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-08

권 26 페이지 1021 ~ 1024

Stereoselective synthesis of 1 '-functionalized-4 '-thionucleosides. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-08

권 26 페이지 1011 ~ 1014

Design, enantiopure synthesis, and biological evaluation of novel iso-D-2 ',3 '-dideoxy-3 '-fluorothianucleoside derivatives as a bioisostere of lamivudine. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-08

권 26 페이지 911 ~ 915

Synthesis of enantiopure pseudo-L-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-08

권 26 페이지 975 ~ 978

Asymmetric synthesis of novel pseudo-D-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-08

권 26 페이지 1001 ~ 1004

Asymmetric synthesis of apio fluoroneplanocin a analogs as potential AdoHcy hydrolase inhibitor. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-08

권 26 페이지 943 ~ 947

Discovery of a new nucleoside template for human A3 adenosine receptor ligands: D-4′-thioadenosine derivatives without 4′-hydroxymethyl group as highly potent and selective antagonists. JOURNAL OF MEDICINAL CHEMISTRY, AMER CHEMICAL SOC, 2007-07

권 50 호 14 페이지 3159 ~ 3162

Stereoselective synthesis of homo-apioneplanocin A as potential inhibitor of S-adenosylhomocysteine hydrolase. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-06

권 26 페이지 729 ~ 732

Synthesis and anti-HCV activity of 2 '-beta-hydroxymethylated nucleosides. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-06

권 26 페이지 725 ~ 728

Asymmetric synthesis of novel apio carbocyclic nucleoside analogues as potential antiviral and antitumor agent. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-06

권 26 페이지 721 ~ 724

Synthesis of N6-Substituted 3′-ureidoadenosine derivatives as highly potent agonists at the mutant A3 adenosine receptor. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-06

권 26 호 6-7 페이지 717 ~ 719

Synthesis and antitumor activity of fluorocyclopentenyl-pyrimidines. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2007-06

권 26 페이지 713 ~ 716

Design, synthesis, and biological evaluation of novel iso-D-2,3 '-dideoxy-3 '-fluorothianucleoside derivatives. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2007-01

권 15 페이지 227 ~ 234

Synthesis of novel L-N-MCd4T as a potent anti-HIV agent. ORGANIC & BIOMOLECULAR CHEMISTRY, ROYAL SOC CHEMISTRY, 2006-11

권 4 호 23 페이지 4065 ~ 4067

Stereoselective synthesis of 2 '-C-methyl-cyclopropyl-fused carbanucleosides as potential anti-HCV agents. ORGANIC LETTERS, AMER CHEMICAL SOC, 2006-10

권 8 페이지 5081 ~ 5083

Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2006-08

권 16 페이지 4190 ~ 4194

Design, synthesis, and biological activity of N6-substituted-4′-thioadenosines at the human A3 adenosine receptor. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2006-07

권 14 호 14 페이지 4718 ~ 4730

Asymmetric synthesis of homo-apioneplanocin A from D-ribose. TETRAHEDRON, PERGAMON-ELSEVIER SCIENCE LTD, 2006-06

권 62 페이지 6339 ~ 6342

Structure-activity relationships of 2-chloro-N6-substituted- 4′-thioadenosine-5′-uronamides as highly potent and selective agonists at the human A3 adenosine receptor. JOURNAL OF MEDICINAL CHEMISTRY, AMER CHEMICAL SOC, 2006-01

권 49 호 1 페이지 273 ~ 281

A highly efficient synthesis of unnatural L-sugars from D-ribose. TETRAHEDRON LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2005-08

권 46 호 35 페이지 5903 ~ 5905

Stereoselective synthesis of conformationally rigid apio carbanucleosides as potential antiviral agents. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2005-07

권 24 호 7 페이지 709 ~ 711

Structure-activity relationship of 5'-substituted fluoro-neplanocin A analogues as potent inhibitors of S-adenosylhomocysteine hydrolase. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2005-07

권 24 호 7 페이지 707 ~ 708

Stereoselective synthesis of 3-hydroxymethyl-D-cyclopentenone, the versatile intermediate for the synthesis of carbocyclic nucleosides. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, MARCEL DEKKER INC, 2005-07

권 24 호 7 페이지 611 ~ 613

Synthesis of novel apio carbocyclic nucleoside analogues as selective A3 adenosine receptor agonists. JOURNAL OF ORGANIC CHEMISTRY, AMER CHEMICAL SOC, 2005-06

권 70 호 13 페이지 5006 ~ 5013

A new synthetic route to (north)-methanocarba nucleosides designed as A3 adenosine receptor agonists. JOURNAL OF ORGANIC CHEMISTRY, AMER CHEMICAL SOC, 2005-01

권 70 호 2 페이지 439 ~ 447

Synthesis of 5'-substituted fluoro-neplanocin A analogues: importance of a hydrogen bonding donor at 5'-position for the inhibitory activity of S-adenosylhomocysteine hydrolase. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2004-11

권 14 호 22 페이지 5641 ~ 5644

Recent advances in 4'-thionucleosides as potential antiviral and antitumor agents. CURRENT MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBL LTD, 2004-10

권 11 호 19 페이지 2585 ~ 2637

Preparative synthesis of the key intermediate, (4R,5R)-3-benzyloxymethyl-4,5-isopropylidenedioxycyclopent-2-enone for carbocyclic nucleosides. CHEMISTRY LETTERS, CHEMICAL SOC JAPAN, 2004-05

권 33 호 5 페이지 506 ~ 507

Preparative and Stereoselective synthesis of the versatile intermediate for carbocyclic nucleosides: Effects of the bulky protecting groups to enforce facial selectivity. JOURNAL OF ORGANIC CHEMISTRY, AMER CHEMICAL SOC, 2004-04

권 69 호 7 페이지 2634 ~ 2636

Synthesis of fluorinated cyclopentenyladenine as potent inhibitor of S-adenosylhomocysteine hydrolase. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2004-03

권 14 호 9 페이지 2091 ~ 2093

Synthesis of D- and L-apio nucleoside analogues with 2'-hydroxyl group as potential anti-HIV agents. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2004-03

권 12 호 5 페이지 1101 ~ 1109

Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety. BIOCHEMICAL PHARMACOLOGY, PERGAMON-ELSEVIER SCIENCE LTD, 2004-03

권 67 호 5 페이지 893 ~ 901

Synthesis and biological evaluation of novel tert-azido or tert-aminosubstituted penciclovir analogs. ORGANIC & BIOMOLECULAR CHEMISTRY, ROYAL SOC CHEMISTRY, 2004-02

권 2 호 8 페이지 1164 ~ 1168

Synthesis and Biological Evaluation of Halo-neplanocin as Novel Mechanism-Based Inhibitors of S-Adenosylhomocysteine Hydrolase. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS., MARCEL DEKKER INC, 2003-09

권 22 호 58 페이지 589 ~ 592

Synthesis and Biological Evaluation of Pyrimidine Nucleosides Fused with 3,4-Tetrahydrofuran Ring. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS., MARCEL DEKKER INC, 2003-09

권 22 호 58 페이지 719 ~ 721

Synthesis of 5-Azacytidine Nucleosides with Rigid Moiety as Potential Antitumor Agents. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS., MARCEL DEKKER INC, 2003-09

권 22 호 58 페이지 915 ~ 917

Synthesis of Halogenated 9-(Dihydroxycyclopent-4-enyl)Adenines and Their Inhibitory Activities Against S-Adenosyhomocysteine Hydrolase. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS., MARCEL DEKKER INC, 2003-09

권 22 호 58 페이지 919 ~ 921

Design and Synthesis of A3 Adenosine Receptor Ligands, 3-Fluoro Analogues of Cl-IB-MECA. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS., MARCEL DEKKER INC, 2003-09

권 22 호 58 페이지 923 ~ 925

Design and Synthesis of A3 Adenosine Receptor Ligands, 2-Fluoro Analogues of Cl-IB-MECA. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS., MARCEL DEKKER INC, 2003-09

권 22 호 58 페이지 927 ~ 930

Design, Synthesis, and In Vitro Evaluation of Apio Analogue of Neplanocin A. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS., MARCEL DEKKER INC, 2003-09

권 22 호 58 페이지 1475 ~ 1477

Recent Advances in the Synthesis of Conformationally Locked Nucleosides and Their Success in Probing the Critical Question of Conformational Preferences by Their Biological Targets. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS., MARCEL DEKKER INC, 2003-09

권 22 호 58 페이지 547 ~ 557

N6-Substituted D-4`-thioadenosine-5`-methyluronamides: potent and selective agonists at the human A3 adenosine receptor. JOURNAL OF MEDICINAL CHEMISTRY, AMER CHEMICAL SOC, 2003-08

권 46 호 18 페이지 3775 ~ 3777

Design, Synthesis and Binding Affinity of 3`-Fluoro Analogues of Cl-IB-MECA as Adenosine A3 Receptor Ligands. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2003-03

권 13 호 5 페이지 817 ~ 820

Design, Synthesis, and Biological Evaluation of Fluoroneplanocin A as the Novel Mechanism-Based Inhibitor of S-Adenosylhomocysteine Hydrolase. JOURNAL OF MEDICINAL CHEMISTRY, AMER CHEMICAL SOC, 2003-01

권 46 호 2 페이지 201 ~ 203

Stereoselective Synthesis of a Novel Apio Analog of Neplanocin A as Potential S-Adenosylhomocysteine Hydrolase Inhibitor.. ORGANIC LETTERS, AMER CHEMICAL SOC, 2002-10

권 4 호 20 페이지 3501 ~ 3503

Novel D-2'-Azido-2',3'-dideoxyarabinofuranosyl-4'-thiopyrimidines and purines.. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON-ELSEVIER SCIENCE LTD, 2002-09

권 12 호 17 페이지 2403 ~ 2406

Enantioselective Synthesis of Bicyclo[3.1.0]hexane Carbocyclic Nucleosides via a Lipase-Catalyzed Asymmetric Acetylation. Characterization of an Unusual Acetal Byproduct.. Journal of Organic Chemistry, 미국화학회, 2002-08

권 67 호 17 페이지 5938 ~ 5945

Synthesis of 2 ',3 '-didehydro-2 ',3 '-dideoxy-2 '-fluoro apionucleosides as potential antiviral agents. JOURNAL OF THE CHEMICAL SOCIETY - PERKIN TRANSACTION 1, ROYAL SOC CHEMISTRY, 2002-08

권 182 페이지 1800 ~ 1804

Improved and alternative synthesis of D- and L-cyclopentenone derivatives, the versatile intermediates for the synthesis of carbocyclic nucleosides. TETRAHEDRON-ASYMMETRY, PERGAMON-ELSEVIER SCIENCE LTD, 2002-06

권 13 페이지 1189 ~ 1193

Synthesis and biological evaluation of novel thioapio dideoxynucleosides. BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON-ELSEVIER SCIENCE LTD, 2002-05

권 10 페이지 1499 ~ 1507

Synthesis of novel D-2′-Deoxy-2′-C-difluoromethylene-4′-thiocytidine as a potential antitumor agent. ORGANIC LETTERS, AMER CHEMICAL SOC, 2002-02

권 4 호 4 페이지 529 ~ 531